ACUTE BRONCHITIS This refers to an acute infection of the bronchial mucosa. It is often found in association with upper respiratory tract infection. Most of the cases are viral and do not require antibiotics for treatment. Antibiotics should however be prescribed if the patient is very ill or breathless or has an underlying illness like malnutrition, measles, rickets, anaemia, diabetes mellitus, chronic bronchitis, HIV/AIDS. CAUSES · Bacteria e.g. Streptococci, Staph. aureus, H. influenza · Viruses e.g. Influenza virus SYMPTOMS · Initial dry cough, later productive · Anterior chest pain aggravated by coughing · Low grade fever SIGNS · Fever · Rhinorrhoea · Crepitations and rhonchi INVESTIGATIONS · FBC · Sputum culture TREATMENT Treatment objectives · To relieve symptoms · To treat suspected bacterial infection Non-pharmacological treatment · Bed rest · Keep well hydrated · Give humidified air if possible Pharmacological treatment (Evidence rating: C) · Paracetamol, oral, Adults 500 mg-1g 6-8 hourly 135 DISORDERS OF THE RESPIRATORY SYSTEM Children 6-12 years; 250-500 mg 6-8 hourly 1-5 years; 120-250 mg 6-8 hourly 3 months-1 year; 60-120 mg 6-8 hourly Plus · Amoxicillin (Amoxycillin), oral, Adults 500 mg 8 hourly for 7 days Children 6-12 years; 250 mg 8 hourly for 7 days 1-5 years; 125 mg 8 hourly for 7 days <1 year; 62.5 mg 8 hourly for 7 days Or Co-amoxiclav, oral, Adults One 500/125 tablet 12 hourly Children > 12 years; One 500/125 tablet 12 hourly for 7 days 6-12 years; 5 ml of 400/57 suspension 12 hourly for 7 days 1-6years; 2.5ml of 400/57 suspension 12 hourly for 7 days 1month-1 year; 0.25ml/kg body weight of 125/31 suspension 8 hourly for 7 days < 1 month; 0.25ml/kg body weight of 125/31 suspension 8 hourly for 7 days Note Double the dose of the above antibiotic in severe infections For individuals allergic to penicillin: · Erythromycin, oral, Adults 250-500 mg 6 hourly 7 days Children 8-18 years; 250-500 mg 6 hourly 7 days 2-8 years; 250 mg 6 hourly 7 days 6 months-2 years; 125 mg 6 hourly 7 days Or Azithromycin, oral, Adults 500 mg once daily for 3 days Children 10 mg/kg once daily for 3 days